Angry Dr. Mario / Dr. Mario's Origin Story AI Video

Angry Dr. Mario or Dr. Mario's Origin Story AI Video refers to an image of Dr. Mario with an angry expression on his face taken from an AI-generated video offering the origin story of Dr. Mario. The video went viral on X / Twitter in mid-May 2024 and inspired memes over the following days, including redraws of the angry Dr. Mario face. Along with the angry Dr. Mario face, an image of Luigi laying in a hospital bed also became the subject of redraws, with another image of Dr. Mario holding a pill labeled "fentanyl" also garnering memetic use.